Created by Zoe Robyn and Carlton Cuse , Pulsehas been compared to earlyGrey ’s Anatomy , with one lead saying “ It ’s sexy , and it ’s romantic , and it ’s striking . ” The show ’s outline certainly promises wad of tenseness , pore on Dr. Danielle Simms , who is circumstantially promoted to Chief Resident after her ex - partner is suspended from the position . Still grappling with the side effect of their separation , Simms must not only demonstrate herself to her Superior and colleagues but also pilot the challenges of play alongside her former dear — just as a rude disaster create an outpouring of critical pillowcase .
Actress : Willa Fitzgerald was comport in Nashville , Tennesse , andbroke big in MTV’sScream : The TV Series , where she played the go final girl , Emma Duval . Since then , she ’s star in BBC One ’s miniseries dramatization ofLittle Womenand USA web ’s adaptation of Megan Abbott ’s teen closed book thriller , Dare Me . Most recently , she encounter The Lady inStrange Darlingand was constitute at the Critics Choice Awards for portraying Young Madeline inMike Flanagan’sThe evenfall of the House of Usher .
Character : Willa Fitzgerald leadsPulse ’s cast , playingDr . Danielle Simms , a third - year resident at Maguire Medical Center . After the side effect of a very complicated wild-eyed relationship occur to lightness , Simms is suddenly encourage and ram to continue working with her ex - partner , Dr. Xander Phillips . When a growing storm convey an onrush of trauma cases , she will not only have to prove herself as a medic but as a woman and respectable colleague .
player : Colin Woodell was tolerate in San Francisco , California , and had hisbreakout purpose inThe Originals , playing Aiden in season 2 of the show . He starred inUnfriended : Dark Webas Matias and inPeacock’sThe Continentalas Winston Scott . Notably , he acted alongside Kaley Cuoco in the dark comedy thrillerThe Flight Attendant , which was nominate for the 2025 and 2025 Critics ' Choice Awards . Previously , he had appearance inXOXOandDesignated Survivor .
Character : Colin Woodell partake the lead with Fitzgerald and playsDr . Xander Phillips , former Chief Resident and Danielle ’s x . When he faces a suspension , Phillips ’s respected condition at Maguire Medical Center hang by a screw thread , particularly as his secret family relationship with Simms is exposed to his colleagues . However , when a violent storm hit Miami , he is called back to the hospital , where he will try his best to support Danielle as she fulfill a bigger part , though he may not be able to rent go of his feelings just as easily .
Actress : Justina Machado was born in Chicago , Illinois , andbroke out as Penelope Alvarez in Norman Lear ’s sitcomOne Day at a Time . She ’s had recurring roles inSix Feet Under , Jane the Virgin , andQueen of South , and has made special appearing in a number of TV display , such asLaw & Order , The Fosters , Desperate Housewives , andSwitched at Birth . Machado has already act in several medical dramas , includingERandPrivate Practice . late , she star in Prime Video’sThe Horror of Dolores Roach .
Character : As part ofPulse ’s chief cast of characters , Justina Machado portraysDr . Natalie Cruz , Chair of Surgery and Emergency Medicineat the Miami trauma middle . Cruz chooses Danielle as Dr. Xander Phillips ’ replacement after his suspension , appointing her as Chief Resident . At the same time that she mentor other resident physician amidst a violent storm , she has to deal with the consequences of Phillips and Simms ’ relationship while she actively tries to stand the latter ’s focus on her calling .
Jessie T. Usher as Sam Elijah : the actor is most known for playing A - gearing in Amazon Original’sThe Boys . Other noteworthy credits includeSmile , Camila Mendes’Dangerous Lies , Survivor ’s self-reproach , Independence Day : revival , andLevel Up . InPulse , Usher playsSam Elijah , Danielle ’s close friend and workfellow , who endure by her as her world implodes .
Jack Bannon as Tom Cole : Jack Bannonbroke big by playing Alfred inPennyworth , also get laid asPennyworth : The Origin of Batman ’s Butler . He also had fall back function inMedici , Endeavour , andThe dark . In Netflix ’s Modern medical dramatic event , Bannon portrays Tom Cole , a fellow resident at Maguire Medical Center who seek the verity behind Dr. Xander Philipps ' suspension while he make out with his personal problem .
Jessy Yates as Harper Simms : the actress is a recent alumnus of Yale School of Drama . As an emerge performer , her roles include playing Morgan inMeand being the voice of Rae inSkillsville . In the Netflix show , she plays Dr. Harper Simms , maybe a sibling to Danielle , and an emergency medic with her own narration .
Néstor Carbonell as Dr. Ruben Soriano : Carbonell has received nomination for his use as Richard Alpert inLost , Luis Rivera inSuddenly Susan , Vasco RodriguesShōgun , Sheriff Alex Romero inBates Motel , and Yanko Flores in Apple TV+’sThe Morning Show . InPulse , he plays Dr. Ruben Soriano , a top medical officer who does n’t agree with Cruz ’s nominate Simms as Chief Resident .
Max ’s new medical series is getting good reviews , but now a real - life story doctor analyse how accurate the show is with the infirmary environment .
Jessica Rothe as Cass Himmelstein : Rothe isbest know for starring inHappy Death Dayand its continuation as Tree Gelbman . She behave alongside Dakota Fanning inPlease Stand Byand had notable appearance inValley Girl , Amazon Prime’sUtopia , andBoy Kills World .
Daniela Nieves as Camila Perez : the actress break up out playing Patricia Giraldo and Adriana Montiel in the easy lay operasLa Viuda de BlancoandEl Rostro de Analía . She also had recur function inUna Maid en Manhattan , Nickelodeon’sEvery Witch Way , WITS Academy , Five item , Save Me , and Peacock’sVampire Academy .
Chelsea Muirhead as Sophie Chan : An come forth actress , Muirhead has acted in a few TV pic and short photographic film . Most notably , she work Sasha inSlo Pitch , Yan Mi inWarrior , and Lissa Dragomir in Peacock’sVampire Academy . The actress plays Sophie Chan inPulse , a house physician at Maguire Medical Center who ’s being mentor by Dr. Natalie Cruz .